OFFICIAL NOTICE CONTENT
Opportunity description
1.0 DESCRIPTION This is a combined synopsis/solicitation for commercial products prepared in accordance with RFO FAR Part 12. This announcement constitutes the only solicitation. Offers are being requested, and a separate written solicitation will not be issued. Solicitation No. 75N98026Q01226 is issued as a Request for Quotation (RFQ) for Promega assay reagents to support Complement-ARIE mechanistic toxicology research. The Government intends to award a purchase order on a sole-source basis to Promega Corporation based on the Government's determination that Promega Corporation is the only source identified as capable of satisfying the Government's requirements. However, all responsible sources may submit a quotation that demonstrates their ability to satisfy the complete requirements identified in this RFQ and the attached requirements document. All timely quotations will be considered by the Government. This RFQ is being posted to the Governmentwide Point of Entry (GPE) in accordance with RFO FAR 5.201. This acquisition will be conducted in accordance with RFO FAR Part 12 � Acquisition of Commercial Products and Commercial Services, using the simplified procedures at RFO FAR 12.201-1. The Department of Health and Human Services (HHS), National Institutes of Health (NIH), National Institute of Environmental Health Sciences (NIEHS), intends to procure, on a sole source basis, Promega assay reagents from the manufacturer, Promega Corporation, 2800 Woods Hollow Road, Madison, Wisconsin 53711. The Promega assay reagents are required to support Complement-ARIE research conducted by the National Center for Advancing Translational Sciences (NCATS) and NIEHS through the Mechanistic Toxicology Branch (MTB) within the Division of Translational Toxicology (DTT). The reagents will be used to assess cell viability, liver injury, liver function, oxidative stress, antioxidant responses, and cellular bioenergetics in human three-dimensional microphysiological systems and will complement cell painting and omics endpoints. Continued use of the specified assay reagents is necessary to support the established experimental approach, maintain consistency and comparability of research results, and provide the required sensitivity for evaluating toxicity responses in small three-dimensional microtissue models. Due to the specialized nature of the Complement-ARIE research and the Government�s requirement for the specific combination of assay reagents, luminescence/chemiluminescence-based detection, toxicological endpoints, and compatibility with the established experimental approach, the Government intends to procure these supplies on a sole-source basis from Promega Corporation. Promega Corporation manufactures the assay reagents identified in the Government�s requirement and, based on the market research conducted, is the only source identified that can satisfy the Government�s requirements. The Government has determined that these requirements are necessary to support the established research methodology, maintain comparability and reproducibility of results, and enable integration of the assay results with existing cell painting and omics-based analyses. The contractor shall provide the Promega assay reagents identified in the Government�s requirement and associated quotation. The reagents shall support measurement of cell viability, liver injury, liver function, oxidative stress, antioxidant responses, and cellular bioenergetics in human three-dimensional microphysiological systems. The contractor shall deliver the required supplies to NIEHS in Rall Building 101, laboratories E144-146, located at 111 T.W. Alexander Drive, Research Triangle Park, North Carolina 27709. Acceptance will be demonstrated by successful delivery and the successful performance of the specified assays within the NIEHS laboratory. There is no travel for this purchase. Required delivery date: September 25, 2026 Delivery Location: NIEHS, Rall Building 101, Laboratories E144-146, 111 T.W. Alexander Drive, Research Triangle Park, NC 27709 The applicable NAICS code is 325413 � In-Vitro Diagnostic Substance Manufacturing. The applicable PSC is 6550 � In Vitro Diagnostic Substances, Reagents, Test Kits and Sets. Please see the attached requirements document titled �75N98026Q01226 � Requirements Document� for additional information. 2.0 UNIQUE QUALIFICATIONS OF THE CONTRACTOR The proposed contractor, Promega Corporation, is the manufacturer of the required assay reagents for the Complement-ARIE research conducted by NCATS and NIEHS. The required supplies involve specialized assay reagents designed to measure cell viability, liver injury, liver function, oxidative stress, antioxidant responses, and cellular bioenergetics in human three-dimensional microphysiological systems. The requested reagents also provide luminescence/chemiluminescence-based detection and are intended to complement established cell-painting and omics-based endpoints. The Promega assay reagents are specialized research products that are required to support the Government�s established experimental approach for evaluating toxicity-induced liver injury and associated cellular responses in human three-dimensional microphysiological systems. Due to the specific combination of required toxicological endpoints, detection technology, and compatibility with the established Complement-ARIE research methodology, use of an alternate source could require modifications to the experimental design and methodologies, affect assay sensitivity, and reduce the comparability and reproducibility of results across the research program. Accordingly, Promega Corporation is the only identified responsible source capable of providing the complete combination of assay reagents required to meet the Government�s scientific and technical requirements while maintaining the established experimental approach. BASIS FOR AWARD The Government intends to issue a firm-fixed-price purchase order to Promega Corporation. However, all timely quotations received will be considered. To be considered for award, a quotation must demonstrate that the products offered satisfy all the Government's scientific and technical requirements identified in this RFQ and the attached requirements document. Award will be made to the responsible quoter whose quotation satisfies the Government's requirements and whose price is determined fair and reasonable. RESPONSE INSTRUCTIONS The response and any other information furnished must be in writing and must contain material in sufficient detail to allow the Office of Acquisition and Logistics Management (OALM) to determine whether the respondent can fulfill the requirement. Quotations shall identify the products being offered, manufacturer and part numbers, quantities, unit and total prices, delivery schedule, and sufficient technical information to demonstrate that the products offered satisfy all of the Government's scientific and technical requirements identified in the attached requirements document. All responses must be sent via email to Contract Specialist, Jordan Neal, at Jordan.Neal@nih.gov, copying Contracting Officer, Alice Pag�n Pereira, at Alice.Pagan@nih.gov by no later than 12:00 pm Eastern Time on Monday, September 21, 2026. To be eligible for award, the contractor must be registered in System for Award Management (SAM.gov) in accordance with applicable requirements. Reference: 75N98026Q01226 on all correspondence.
FEDERAL BUYER
Buyer and contracting office
Public points of contact
GOVBIDFIT SCREENING LENS
What deserves attention before you spend bid time
These screening signals are generated from the public notice fields stored for this specific opportunity. They are not eligibility findings or predictions; they are prompts for a faster, more disciplined review of the official solicitation.
This record is in a solicitation stage, so submission instructions, evaluation factors, attachments and amendments should be reviewed before a bid/no-bid decision.
The stored deadline is within three days. Check earlier question, site-visit and attachment requirements immediately; the final response date may not be the first deadline that matters.
No Set aside used is recorded as the set-aside or restriction. Confirm the bidding entity actually satisfies the applicable program and size requirements before investing proposal time.
NAICS 325413 · PSC 6550 is the recorded classification. Use it as a screening clue, then compare the actual scope and deliverables rather than treating the code alone as proof of fit.
GovBidFit has stored substantive notice text for this record, but attachments, clauses, amendments and Q&A can still contain requirements that are not visible in the description alone.
The source data includes 2 public contracting contacts. Use the solicitation's stated communication rules and deadlines before contacting the buyer.
Questions to resolve next
What this opportunity record tells you
SAM.gov identifies this as a combined synopsis/solicitation from HEALTH AND HUMAN SERVICES, DEPARTMENT OF. The record was posted on September 16, 2026 and currently lists September 21, 2026 as the response deadline. GovBidFit keeps source facts separate from its matching guidance so you can see what comes from the federal notice.
The listed product or service classification is NAICS 325413 · PSC 6550. The set-aside field is No Set aside used. These fields help narrow your search, but they do not replace the full solicitation, amendments, attachments, clauses or eligibility language on the official source.
Before deciding to bid
GovBidFit is independent and is not a U.S. government website. GovBidFit stores a structured mirror of SAM.gov public opportunity data in its own database and keeps the compact snapshot as a fallback. The official SAM.gov notice remains the controlling source. The official SAM.gov notice controls if anything here differs from the source or a later amendment.
Open the official SAM.gov notice →